Clean skin using alcohol swab or by washing with soap. Dry thoroughly. Remove backing and apply patch to intact skin, pressing firmly to ensure adhesion. Onset is 1 hour + 30 minutes. Duration: 12 hours. Dosage: 1 ml. Recommended Application Areas: Inside of wrists; top of hands; inside/outside of biceps; outside shoulder; under armpit; back or back of neck below shirt-line; sides of torso; back inside of ankle; top of foot; or wherever patient experiences local muscle soreness, stiffness, pain, or weakness.